4N3B

Crystal Structure of human O-GlcNAc Transferase bound to a peptide from HCF-1 pro-repeat2(1-26)E10Q and UDP-5SGlcNAc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	polymer	723	80974.5	1	UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) In PDB	Homo sapiens (human)	O-GlcNAc transferase subunit p110, O-linked N-acetylglucosamine transferase 110 kDa subunit, OGT
2	B	Host cell factor 1	polymer	26	2693.9	1	UniProt (P51610) In PDB	Homo sapiens
3	A	(2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate	non-polymer		623.4	1	Chemie (12V)
4		water	water		18.0	124	Chemie (HOH)

Sequence modifications

A: 313 - 1031 (UniProt: O15294)

PDB	External Database	Details
Gly 309	-	expression tag
Pro 310	-	expression tag
Gly 311	-	expression tag
Ser 312	-	expression tag

B: 1 - 26 (UniProt: P51610)

PDB	External Database	Details
Gln 10	Glu 1081	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83668.4
Non-Polymers*	Number of molecules	1
	Total formula weight	623.4
All*	Total formula weight	84291.8

*Water molecules are not included.