4N3B
Crystal Structure of human O-GlcNAc Transferase bound to a peptide from HCF-1 pro-repeat2(1-26)E10Q and UDP-5SGlcNAc
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE 12V A 1501 |
| Chain | Residue |
| A | HIS498 |
| A | TYR841 |
| A | LYS842 |
| A | LEU866 |
| A | VAL895 |
| A | ALA896 |
| A | LYS898 |
| A | HIS901 |
| A | ARG904 |
| A | CYS917 |
| A | HIS920 |
| A | PRO559 |
| A | THR921 |
| A | THR922 |
| A | ASP925 |
| A | HOH1611 |
| A | HOH1625 |
| A | HOH1646 |
| A | HOH1687 |
| A | HOH1696 |
| B | PRO7 |
| B | PRO8 |
| A | THR560 |
| B | CYS9 |
| B | GLN10 |
| A | LEU563 |
| A | LEU653 |
| A | GLY654 |
| A | PRO656 |
| A | PHE694 |
| A | GLN839 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:7590226 |
| Chain | Residue | Details |
| B | GLN10 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23103939, ECO:0007744|PDB:4GYW |
| Chain | Residue | Details |
| A | GLN839 | |
| A | LYS842 | |
| A | ALA896 | |
| A | HIS901 | |
| A | HIS920 | |
| A | ASP925 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by AMPK => ECO:0000269|PubMed:24563466, ECO:0000269|PubMed:37541260 |
| Chain | Residue | Details |
| A | THR444 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P56558 |
| Chain | Residue | Details |
| A | TYR979 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: O-linked (GlcNAc) serine; by autocatalysis => ECO:0000269|PubMed:27713473 |
| Chain | Residue | Details |
| A | SER389 |
