4N35
Structure of langerin CRD I313 complexed with GlcNAc-beta1-3Gal-beta1-4Glc-beta-CH2CH2N3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | C-type lectin domain family 4 member K | polymer | 136 | 15561.4 | 4 | UniProt (Q9UJ71) Pfam (PF00059) | Homo sapiens (human) | Langerin |
| 2 | E, F, H (E, F, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 545.5 | 3 | In PDB GlyTouCan (G06239NA) | |||
| 3 | G (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose | branched | 383.3 | 1 | In PDB GlyTouCan (G33476GF) | |||
| 4 | I, J, K, L (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 5 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 591 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 193 - 328 (UniProt: Q9UJ71)
| PDB | External Database | Details |
|---|---|---|
| Ala 278 | Val 278 | variant |
| Ile 313 | Lys 313 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62245.4 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2019.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 160.3 | |
| All* | Total formula weight | 64425.5 |
