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4N0E

Crystal structure of the K345L variant of the Gi alpha1 subunit bound to GDP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35640527.11UniProt (P10824)
Pfam (PF00503)
Rattus norvegicus (brown rat rat rats)Adenylate cyclase-inhibiting G alpha protein
2B
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(A)
waterwater18.0123Chemie (HOH)
Sequence modifications
A: 1 - 354 (UniProt: P10824)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Leu 345Lys 345engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40527.1
Non-Polymers*Number of molecules2
Total formula weight539.3
All*Total formula weight41066.4
*Water molecules are not included.

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PDB entries from 2025-07-16

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