4N0E
Crystal structure of the K345L variant of the Gi alpha1 subunit bound to GDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 356 | 40527.1 | 1 | UniProt (P10824) Pfam (PF00503) | Rattus norvegicus (brown rat rat rats) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A: 1 - 354 (UniProt: P10824)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Leu 345 | Lys 345 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40527.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 539.3 | |
| All* | Total formula weight | 41066.4 |
