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4N0E

Crystal structure of the K345L variant of the Gi alpha1 subunit bound to GDP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AGuanine nucleotide-binding protein G(i) subunit alpha-1polymer35640527.11UniProt (P10824)
Pfam (PF00503)
In PDB
Rattus norvegicus (brown rat rat rats)Adenylate cyclase-inhibiting G alpha protein
2AGUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
3ASULFATE IONnon-polymer96.11Chemie (SO4)
4waterwater18.0123Chemie (HOH)
Sequence modifications
A: 1 - 354 (UniProt: P10824)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Leu 345Lys 345engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40527.1
Non-Polymers*Number of molecules2
Total formula weight539.3
All*Total formula weight41066.4
*Water molecules are not included.

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PDB entries from 2024-07-17

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