4N0D
Crystal structure of the K345L variant of the Gi alpha1 subunit bound to GTPgammaS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 356 | 40527.1 | 1 | UniProt (P10824) Pfam (PF00503) In PDB | Rattus norvegicus (brown rat rat rats) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | A | SULFITE ION | non-polymer | 80.1 | 1 | Chemie (SO3) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | A | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (GSP) | |||
| 5 | water | water | 18.0 | 382 | Chemie (HOH) |
Sequence modifications
A: 1 - 354 (UniProt: P10824)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Leu 345 | Lys 345 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40527.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 643.6 | |
| All* | Total formula weight | 41170.8 |
