4MZV
Crystal structure of extracellular part of human EpCAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Epithelial cell adhesion molecule | polymer | 248 | 28277.0 | 1 | UniProt (P16422) Pfam (PF18635) Pfam (PF00086) Pfam (PF21283) In PDB | Homo sapiens (human) | Ep-CAM, Adenocarcinoma-associated antigen, Cell surface glycoprotein Trop-1, Epithelial cell surface antigen, Epithelial glycoprotein, EGP, Epithelial glycoprotein 314, EGP314, hEGP314, KS 1/4 antigen, KSA, Major gastrointestinal tumor-associated protein GA733-2, Tumor-associated calcium signal transducer 1 |
| 2 | A | DECYL-BETA-D-MALTOPYRANOSIDE | non-polymer | 482.6 | 1 | Chemie (DMU) | |||
| 3 | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A: 24 - 265 (UniProt: P16422)
| PDB | External Database | Details |
|---|---|---|
| Gln 74 | Asn 74 | engineered mutation |
| Gln 111 | Asn 111 | engineered mutation |
| Thr 115 | Met 115 | SEE REMARK 999 |
| Gln 198 | Asn 198 | engineered mutation |
| His 266 | - | expression tag |
| His 267 | - | expression tag |
| His 268 | - | expression tag |
| His 269 | - | expression tag |
| His 270 | - | expression tag |
| His 271 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28277.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 482.6 | |
| All* | Total formula weight | 28759.5 |
