4MZE
Crystal structure of hPIV3 hemagglutinin-neuraminidase, H552Q/Q559R mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hemagglutinin-neuraminidase | polymer | 437 | 48824.4 | 2 | UniProt (P08492) Pfam (PF00423) | Human parainfluenza 3 virus (HPIV-3) | |
| 2 | C (C) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 1 | In PDB GlyTouCan (G80966KZ) | |||
| 3 | D (D) | beta-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G61843VN) | |||
| 4 | E (E) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 5 | F (F) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | G, U (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | H, V, W (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 8 | I, X (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 9 | AA, BA, CA, DA, EA... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 15 | Chemie (EDO) | |||
| 10 | FA, GA, R, S (B, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 11 | T (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 12 | HA, IA (A, B) | water | water | 18.0 | 638 | Chemie (HOH) |
Sequence modifications
A, B: 136 - 572 (UniProt: P08492)
| PDB | External Database | Details |
|---|---|---|
| Gln 552 | His 552 | engineered mutation |
| Arg 559 | Gln 559 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97648.9 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 3262.0 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 2259.0 | |
| All* | Total formula weight | 103169.9 |
