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4MZ5

Structure of importin-alpha: dUTPase NLS complex

Replaces:  4FDR
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, C)
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrialpolymer131384.62UniProt (P33316)Homo sapiensdUTPase, dUTP pyrophosphatase
2C
(E)
Importin subunit alpha-1polymer50955121.31UniProt (P52293)
Pfam (PF01749)
Pfam (PF00514)
Pfam (PF16186)
Mus musculus (mouse)Importin alpha P1, Karyopherin subunit alpha-2, Pendulin, Pore targeting complex 58 kDa subunit, PTAC58, RAG cohort protein 1, SRP1-alpha
3D, E, F
(A, C, E)
waterwater18.0192Chemie (HOH)
Sequence modifications
E: 70 - 528 (UniProt: P52293)
PDBExternal DatabaseDetails
Met 20-expression tag
His 21-expression tag
His 22-expression tag
His 23-expression tag
His 24-expression tag
His 25-expression tag
His 26-expression tag
Ser 27-expression tag
Ser 28-expression tag
Gly 29-expression tag
Leu 30-expression tag
Val 31-expression tag
Pro 32-expression tag
Arg 33-expression tag
Gly 34-expression tag
Ser 35-expression tag
Gly 36-expression tag
Met 37-expression tag
Leu 38-expression tag
Glu 39-expression tag
Thr 40-expression tag
Ala 41-expression tag
Ala 42-expression tag
Ala 43-expression tag
Leu 44-expression tag
Phe 45-expression tag
Glu 46-expression tag
Arg 47-expression tag
Asn 48-expression tag
His 49-expression tag
Met 50-expression tag
Asp 51-expression tag
Ser 52-expression tag
Pro 53-expression tag
Asp 54-expression tag
Leu 55-expression tag
Gly 56-expression tag
Thr 57-expression tag
Asp 58-expression tag
Asp 59-expression tag
Asp 60-expression tag
Asp 61-expression tag
Leu 62-expression tag
Ala 63-expression tag
Met 64-expression tag
Ala 65-expression tag
Asp 66-expression tag
Ile 67-expression tag
Gly 68-expression tag
Ser 69-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight57890.5
All*Total formula weight57890.5
*Water molecules are not included.

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PDB entries from 2024-11-06

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