4MXV
Structure of Lymphotoxin alpha bound to anti-LTa Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D | Lymphotoxin-alpha | polymer | 157 | 17313.3 | 3 | UniProt (P01374) Pfam (PF00229) In PDB | Homo sapiens (human) | LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1 |
| 2 | E, L, X | anti-Lymphotoxin alpha antibody light chain | polymer | 211 | 23065.5 | 3 | Homo sapiens (human) | anti-LT-alpha antibody light chain | |
| 3 | F, H, Y | anti-Lymphotoxin alpha antibody heavy chain | polymer | 213 | 22890.7 | 3 | Homo sapiens (human) | anti-LT-alpha antibody heavy chain |
Sequence modifications
A, B, D: 28 - 171 (UniProt: P01374)
| PDB | External Database | Details |
|---|---|---|
| Ala 15 | - | expression tag |
| Asp 16 | - | expression tag |
| Leu 17 | - | expression tag |
| Gly 18 | - | expression tag |
| Ser 19 | - | expression tag |
| Asp 20 | - | expression tag |
| Tyr 21 | - | expression tag |
| Lys 22 | - | expression tag |
| Asp 23 | - | expression tag |
| Asp 24 | - | expression tag |
| Asp 25 | - | expression tag |
| Asp 26 | - | expression tag |
| Lys 27 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 189808.8 | |
| All* | Total formula weight | 189808.8 |
