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4MXV

Structure of Lymphotoxin alpha bound to anti-LTa Fab

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, D)
Lymphotoxin-alphapolymer15717313.33UniProt (P01374)
Pfam (PF00229)
Homo sapiens (human)LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1
2D, F, H
(E, L, X)
anti-Lymphotoxin alpha antibody light chainpolymer21123065.53Homo sapiens (human)anti-LT-alpha antibody light chain
3E, G, I
(F, H, Y)
anti-Lymphotoxin alpha antibody heavy chainpolymer21322890.73Homo sapiens (human)anti-LT-alpha antibody heavy chain
Sequence modifications
A, B, D: 28 - 171 (UniProt: P01374)
PDBExternal DatabaseDetails
Ala 15-expression tag
Asp 16-expression tag
Leu 17-expression tag
Gly 18-expression tag
Ser 19-expression tag
Asp 20-expression tag
Tyr 21-expression tag
Lys 22-expression tag
Asp 23-expression tag
Asp 24-expression tag
Asp 25-expression tag
Asp 26-expression tag
Lys 27-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains9
Total formula weight189808.8
All*Total formula weight189808.8
*Water molecules are not included.

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PDB entries from 2025-06-25

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