4MXE

Human ESCO1 (Eco1/Ctf7 ortholog), acetyltransferase domain in complex with acetyl-CoA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	N-acetyltransferase ESCO1	polymer	206	23998.8	2	UniProt (Q5FWF5) Pfam (PF13880)	Homo sapiens (human)	CTF7 homolog 1, Establishment factor-like protein 1, EFO1p, hEFO1, Establishment of cohesion 1 homolog 1, ECO1 homolog 1, ESO1 homolog 1
2	C, D (A, B)	ACETYL COENZYME *A	non-polymer		809.6	2	Chemie (ACO)
3	E, F (A, B)	water	water		18.0	20	Chemie (HOH)

Sequence modifications

A, B: 654 - 836 (UniProt: Q5FWF5)

PDB	External Database	Details
Met 631	-	expression tag
His 632	-	expression tag
His 633	-	expression tag
His 634	-	expression tag
His 635	-	expression tag
His 636	-	expression tag
His 637	-	expression tag
Ser 638	-	expression tag
Ser 639	-	expression tag
Gly 640	-	expression tag
Val 641	-	expression tag
Asp 642	-	expression tag
Leu 643	-	expression tag
Gly 644	-	expression tag
Thr 645	-	expression tag
Glu 646	-	expression tag
Asn 647	-	expression tag
Leu 648	-	expression tag
Tyr 649	-	expression tag
Phe 650	-	expression tag
Gln 651	-	expression tag
Ser 652	-	expression tag
Met 653	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47997.7
Non-Polymers*	Number of molecules	2
	Total formula weight	1619.1
All*	Total formula weight	49616.8

*Water molecules are not included.