4MXE

Human ESCO1 (Eco1/Ctf7 ortholog), acetyltransferase domain in complex with acetyl-CoA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	N-acetyltransferase ESCO1	polymer	206	23998.8	2	UniProt (Q5FWF5) Pfam (PF13880)	Homo sapiens (human)	CTF7 homolog 1, Establishment factor-like protein 1, EFO1p, hEFO1, Establishment of cohesion 1 homolog 1, ECO1 homolog 1, ESO1 homolog 1
2	C, D (A, B)	ACETYL COENZYME *A	non-polymer		809.6	2	Chemie (ACO) PubChem (25210474) PubChem (24860528) PubChem (53393727) PubChem (56846401) PubChem (44141873) PubChem (45254004) PubChem (444493) PubChem (53245716) PubChem (87656764) PubChem (181) PubChem (6302) PubChem (87656765) PubChem (89102998) PubChem (91746285) PubChem (6857822) PubChem (6917106) PubChem (134956084) PubChem (10079099) PubChem (124511019) PubChem (11987898) PubChem (16061174) PubChem (124931617) PubChem (129274027) PubChem (154496096) PubChem (162968672) PubChem (170108977)
3	E, F (A, B)	water	water		18.0	20	Chemie (HOH)

Sequence modifications

A, B: 654 - 836 (UniProt: Q5FWF5)

PDB	External Database	Details
Met 631	-	expression tag
His 632	-	expression tag
His 633	-	expression tag
His 634	-	expression tag
His 635	-	expression tag
His 636	-	expression tag
His 637	-	expression tag
Ser 638	-	expression tag
Ser 639	-	expression tag
Gly 640	-	expression tag
Val 641	-	expression tag
Asp 642	-	expression tag
Leu 643	-	expression tag
Gly 644	-	expression tag
Thr 645	-	expression tag
Glu 646	-	expression tag
Asn 647	-	expression tag
Leu 648	-	expression tag
Tyr 649	-	expression tag
Phe 650	-	expression tag
Gln 651	-	expression tag
Ser 652	-	expression tag
Met 653	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47997.7
Non-Polymers*	Number of molecules	2
	Total formula weight	1619.1
All*	Total formula weight	49616.8

*Water molecules are not included.