4MXE
Human ESCO1 (Eco1/Ctf7 ortholog), acetyltransferase domain in complex with acetyl-CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000785 | cellular_component | chromatin |
| A | 0006275 | biological_process | regulation of DNA replication |
| A | 0007062 | biological_process | sister chromatid cohesion |
| A | 0034421 | biological_process | post-translational protein acetylation |
| B | 0000785 | cellular_component | chromatin |
| B | 0006275 | biological_process | regulation of DNA replication |
| B | 0007062 | biological_process | sister chromatid cohesion |
| B | 0034421 | biological_process | post-translational protein acetylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ACO A 901 |
| Chain | Residue |
| A | ILE769 |
| A | SER785 |
| A | SER809 |
| A | THR812 |
| A | ASP814 |
| A | LEU817 |
| A | PHE818 |
| A | GLN821 |
| A | ILE772 |
| A | TRP773 |
| A | VAL774 |
| A | ARG779 |
| A | ARG780 |
| A | LYS781 |
| A | LYS782 |
| A | ALA784 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ACO B 901 |
| Chain | Residue |
| B | ILE769 |
| B | ILE772 |
| B | TRP773 |
| B | VAL774 |
| B | ARG779 |
| B | ARG780 |
| B | LYS781 |
| B | LYS782 |
| B | ALA784 |
| B | SER785 |
| B | SER809 |
| B | THR812 |
| B | ASP814 |
| B | LEU817 |
| B | PHE818 |
| B | GLN821 |
| B | HOH1005 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27112597","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27803161","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4MXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5T53","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
