4MWI
Crystal structure of the human MLKL pseudokinase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mixed lineage kinase domain-like protein | polymer | 294 | 33567.8 | 1 | UniProt (Q8NB16) Pfam (PF07714) | Homo sapiens (human) | |
| 2 | B (A) | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol | non-polymer | 368.5 | 1 | Chemie (PXN) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | water | water | 18.0 | 325 | Chemie (HOH) |
Sequence modifications
A: 183 - 471 (UniProt: Q8NB16)
| PDB | External Database | Details |
|---|---|---|
| Gly 178 | - | expression tag |
| Ala 179 | - | expression tag |
| Met 180 | - | expression tag |
| Gly 181 | - | expression tag |
| Ser 182 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33567.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 460.6 | |
| All* | Total formula weight | 34028.3 |
