4MVT

Crystal structure of SUMO E3 Ligase PIAS3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	E3 SUMO-protein ligase PIAS3	polymer	374	41929.0	4	UniProt (Q9Y6X2) Pfam (PF14324) Pfam (PF02891) In PDB	Homo sapiens (human)	Protein inhibitor of activated STAT protein 3
2	A, D, B, C	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	A, C	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	C, A, D, B	UNKNOWN ATOM OR ION	non-polymer			32	Chemie (UNX)
5		water	water		18.0	146	Chemie (HOH)

Sequence modifications

A, B, C, D: 112 - 467 (UniProt: Q9Y6X2)

PDB	External Database	Details
Met 94	-	expression tag
His 95	-	expression tag
His 96	-	expression tag
His 97	-	expression tag
His 98	-	expression tag
His 99	-	expression tag
His 100	-	expression tag
Ser 101	-	expression tag
Ser 102	-	expression tag
Gly 103	-	expression tag
Arg 104	-	expression tag
Glu 105	-	expression tag
Asn 106	-	expression tag
Leu 107	-	expression tag
Tyr 108	-	expression tag
Phe 109	-	expression tag
Gln 110	-	expression tag
Gly 111	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	167715.9
Non-Polymers*	Number of molecules	38
	Total formula weight	332.5
All*	Total formula weight	168048.5

*Water molecules are not included.