4MSV

Crystal structure of FASL and DcR3 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Tumor necrosis factor receptor superfamily member 6B	polymer	174	19044.2	1	UniProt (O95407) Pfam (PF00020)	Homo sapiens (human)	Decoy receptor 3, DcR3, Decoy receptor for Fas ligand, M68
2	B (A)	Tumor necrosis factor ligand superfamily member 6	polymer	152	17345.0	1	UniProt (P48023) Pfam (PF00229)	Homo sapiens (human)	Apoptosis antigen ligand, APTL, CD95 ligand, CD95-L, Fas antigen ligand, Fas ligand, FasL, Tumor necrosis factor ligand superfamily member 6, membrane form, Tumor necrosis factor ligand superfamily member 6, soluble form, Receptor-binding FasL ectodomain, Soluble Fas ligand, sFasL, ADAM10-processed FasL form, APL, FasL intracellular domain, FasL ICD, SPPL2A-processed FasL form, SPA
3	C (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	D (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	E, F (B, A)	water	water		18.0	63	Chemie (HOH)

Sequence modifications

B: 30 - 195 (UniProt: O95407)

PDB	External Database	Details
Thr 196	-	expression tag
Gly 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
His 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	36389.2
Non-Polymers*	Number of molecules	2
	Total formula weight	116.4
All*	Total formula weight	36505.6

*Water molecules are not included.