4MSV

Crystal structure of FASL and DcR3 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005164	molecular_function	tumor necrosis factor receptor binding
A	0006915	biological_process	apoptotic process
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 301

Chain	Residue
B	CYS132
B	PRO133
B	ALA136
B	SER159
B	SER161
B	HOH424

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 301

Chain	Residue
A	LEU222
B	LEU85
B	ARG89
A	ASN215
A	TYR218
A	GLN220

---

Functional Information from PROSITE/UniProt

site_id	PS00251
Number of Residues	17
Details	THD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. LvINeTGLYFVysKVyF

Chain	Residue	Details
A	LEU181-PHE197

---

site_id	PS00652
Number of Residues	44
Details	TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. CgpcpprHytqfwnylerCryCnvlCgereeeara..Chath..NRAC

Chain	Residue	Details
B	CYS70-CYS113

---

site_id	PS01186
Number of Residues	14
Details	EGF_2 EGF-like domain signature 2. CrCrtGFfahagf..C

Chain	Residue	Details
B	CYS113-CYS126

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	41
Details	Repeat: {"description":"TNFR-Cys 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	35
Details	Repeat: {"description":"TNFR-Cys 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	136
Details	Domain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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