4MQK
Carbonmonoxy Structure of the Human Fetal Hemoglobin Mutant HbF Toms River alphawtgammaV67M
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Hemoglobin subunit alpha | polymer | 141 | 15150.4 | 4 | UniProt (P69905) Pfam (PF00042) | Homo sapiens (human) | Alpha-globin, Hemoglobin alpha chain |
| 2 | B, D, F, H (B, D, F, H) | Hemoglobin subunit gamma-2 | polymer | 146 | 16049.3 | 4 | UniProt (P69892) Pfam (PF00042) | Homo sapiens (human) | Gamma-2-globin, Hb F Ggamma, Hemoglobin gamma-2 chain, Hemoglobin gamma-G chain |
| 3 | I, K, M, O, Q... (A, B, C, D, E...) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 8 | Chemie (HEM) | |||
| 4 | J, L, N, P, S... (A, B, C, D, F...) | CARBON MONOXIDE | non-polymer | 28.0 | 6 | Chemie (CMO) | |||
| 5 | AA, BA, CA, DA, W... (E, F, G, H, A...) | water | water | 18.0 | 284 | Chemie (HOH) |
Sequence modifications
B, D, F, H: 1 - 146 (UniProt: P69892)
| PDB | External Database | Details |
|---|---|---|
| Met 67 | Val 68 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 124798.6 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 5100.0 | |
| All* | Total formula weight | 129898.5 |
