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4MPA

Crystal structure of NHERF1-CXCR2 signaling complex in P21 space group

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ANa(+)/H(+) exchange regulatory cofactor NHE-RF1, C-X-C chemokine receptor type 2 chimerapolymer919860.31UniProt (O14745)
UniProt (P25025)
Pfam (PF00595)
In PDB
Homo sapiens (human)NHERF-1, Ezrin-radixin-moesin-binding phosphoprotein 50, EBP50, Regulatory cofactor of Na(+)/H(+) exchanger, Sodium-hydrogen exchanger regulatory factor 1, Solute carrier family 9 isoform A3 regulatory factor 1, CXC-R2, CXCR-2, CDw128b, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8R B, L-8 receptor type 2
2AACETIC ACIDnon-polymer60.11Chemie (ACY)
3ACHLORIDE IONnon-polymer35.51Chemie (CL)
4waterwater18.0158Chemie (HOH)
Sequence modifications
A: 11 - 94 (UniProt: O14745)
PDBExternal DatabaseDetails
Gly 9-expression tag
Met 10-expression tag
A: 95 - 99 (UniProt: P25025)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight9860.3
Non-Polymers*Number of molecules2
Total formula weight95.5
All*Total formula weight9955.8
*Water molecules are not included.

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PDB entries from 2024-05-01

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