4MI5
Crystal structure of the EZH2 SET domain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Histone-lysine N-methyltransferase EZH2 | polymer | 229 | 25971.6 | 1 | UniProt (Q15910) Pfam (PF18264) Pfam (PF00856) In PDB | Homo sapiens (human) | ENX-1, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6 |
2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
3 | A | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
4 | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A: 526 - 751 (UniProt: Q15910)
PDB | External Database | Details |
---|---|---|
Gly 523 | - | expression tag |
Ser 524 | - | expression tag |
Leu 525 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 25971.6 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 488.5 | |
All* | Total formula weight | 26460.2 |