4MI5
Crystal structure of the EZH2 SET domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase EZH2 | polymer | 229 | 25971.6 | 1 | UniProt (Q15910) Pfam (PF18264) Pfam (PF00856) | Homo sapiens (human) | ENX-1, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6 |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C, D, E, F, G... (A) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | I (A) | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A: 526 - 751 (UniProt: Q15910)
| PDB | External Database | Details |
|---|---|---|
| Gly 523 | - | expression tag |
| Ser 524 | - | expression tag |
| Leu 525 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25971.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 488.5 | |
| All* | Total formula weight | 26460.2 |
