4MGH
Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphoribosylformylglycinamidine synthase | polymer | 1303 | 142566.4 | 1 | UniProt (P74881) Pfam (PF18076) Pfam (PF18072) Pfam (PF02769) Pfam (PF22689) Pfam (PF13507) | Salmonella typhimurium | FGAM synthase, FGAMS, Formylglycinamide ribotide amidotransferase, FGARAT, Formylglycinamide ribotide synthetase |
| 2 | B (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | C, D, E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | G (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 5 | H, I, J, K, L... (A) | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
| 6 | U, V, W, X (A) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 7 | AA, BA, Y, Z (A) | XENON | non-polymer | 131.3 | 4 | Chemie (XE) | |||
| 8 | CA (A) | water | water | 18.0 | 518 | Chemie (HOH) |
Sequence modifications
A: 1 - 1295 (UniProt: P74881)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 142566.4 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 2589.5 | |
| All* | Total formula weight | 145155.9 |
