4MEZ
Crystal structure of M68L/M69T double mutant TEM-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Beta-lactamase TEM | polymer | 263 | 28893.9 | 2 | UniProt (P62593) Pfam (PF00144) Pfam (PF13354) In PDB | Escherichia coli | IRT-4, Penicillinase, TEM-1, TEM-16/CAZ-7, TEM-2, TEM-24/CAZ-6, TEM-3, TEM-4, TEM-5, TEM-6, TEM-8/CAZ-2 |
| 2 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | A, B | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 346 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 290 (UniProt: P62593)
| PDB | External Database | Details |
|---|---|---|
| Leu 68 | Met 66 | engineered mutation |
| Thr 69 | Met 67 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57787.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 451.2 | |
| All* | Total formula weight | 58238.9 |
