4MD8
Crystal Structure of full-length symmetric CK2 holoenzyme with mutated alpha subunit (F121E)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Casein kinase II subunit beta | polymer | 215 | 24969.4 | 4 | UniProt (P67870) Pfam (PF01214) | Homo sapiens (human) | CK2 subunit beta, CK II beta, Phosvitin, Protein G5a |
| 2 | E, F, G, H (E, F, G, H) | Casein kinase II subunit alpha | polymer | 391 | 45190.5 | 4 | UniProt (P68400) Pfam (PF00069) | Homo sapiens (human) | CK2 subunit alpha, CK II alpha |
| 3 | I, J, K, L (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
E, F, G, H: 1 - 391 (UniProt: P68400)
| PDB | External Database | Details |
|---|---|---|
| Glu 121 | Phe 121 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 280639.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 280901.3 |
