4MD4
Immune Receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class II histocompatibility antigen, DR alpha chain | polymer | 189 | 21919.6 | 1 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | MHC class II antigen DRA |
| 2 | B (B) | HLA class II histocompatibility antigen, DRB1-4 beta chain | polymer | 200 | 23224.6 | 1 | UniProt (P13760) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) | Homo sapiens (human) | MHC class II antigen DRB1*4, DR-4, DR4 |
| 3 | C (C) | Aggrecan core protein | polymer | 15 | 1802.9 | 1 | UniProt (P16112) | Homo sapiens | Cartilage-specific proteoglycan core protein, CSPCP, Chondroitin sulfate proteoglycan core protein 1, Chondroitin sulfate proteoglycan 1, Aggrecan core protein 2 |
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E, I (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | F, G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 7 | J, K, L (A, B, C) | water | water | 18.0 | 470 | Chemie (HOH) |
Sequence modifications
A: 1 - 181 (UniProt: P01903)
B: 1 - 190 (UniProt: P13760)
C: 1 - 15 (UniProt: P16112)
| PDB | External Database | Details |
|---|---|---|
| Thr 182 | - | expression tag |
| Ser 183 | - | expression tag |
| Gly 184 | - | expression tag |
| Asp 185 | - | expression tag |
| Asp 186 | - | expression tag |
| Asp 187 | - | expression tag |
| Asp 188 | - | expression tag |
| Lys 189 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Thr 191 | - | expression tag |
| Gly 192 | - | expression tag |
| Gly 193 | - | expression tag |
| Asp 194 | - | expression tag |
| Asp 195 | - | expression tag |
| Asp 196 | - | expression tag |
| Asp 197 | - | expression tag |
| Lys 198 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Tyr 4 | Gly 92 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 46947.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 628.6 | |
| All* | Total formula weight | 48000.1 |
