Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Apoptosis regulator Bcl-2 | polymer | 166 | 19357.6 | 2 | UniProt (P10415) Pfam (PF02180) Pfam (PF00452) | Homo sapiens (human) | |
| 2 | C, D (A, B) | 4-[4-({4'-chloro-3-[2-(dimethylamino)ethoxy]biphenyl-2-yl}methyl)piperazin-1-yl]-2-(1H-indol-5-yloxy)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)benzamide | non-polymer | 922.5 | 2 | Chemie (1Y1) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence modifications
A, B: -1 - 32 (UniProt: P10415)
A, B: 89 - 204 (UniProt: P10415)
A, B: 89 - 204 (UniProt: P10415)
| PDB | External Database | Details |
|---|---|---|
| Asp 73 | - | linker |
| Val 74 | - | linker |
| Glu 75 | - | linker |
| Glu 76 | - | linker |
| Asn 77 | - | linker |
| Arg 78 | - | linker |
| Thr 79 | - | linker |
| Glu 80 | - | linker |
| Ala 81 | - | linker |
| Pro 82 | - | linker |
| Glu 83 | - | linker |
| Gly 84 | - | linker |
| Thr 85 | - | linker |
| Glu 86 | - | linker |
| Ser 87 | - | linker |
| Glu 88 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38715.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1845.0 | |
| All* | Total formula weight | 40560.1 |
