Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| B | 0042981 | biological_process | regulation of apoptotic process |
| B | 0043066 | biological_process | negative regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE 1Y1 A 301 |
| Chain | Residue |
| A | ALA97 |
| A | GLY142 |
| A | ARG143 |
| A | ALA146 |
| A | ASN160 |
| A | GLU162 |
| A | SER164 |
| A | PRO165 |
| A | TYR199 |
| A | HOH406 |
| A | HOH519 |
| A | ASP100 |
| A | HOH521 |
| A | HOH531 |
| A | PHE101 |
| A | TYR105 |
| A | ASP108 |
| A | PHE109 |
| A | MET112 |
| A | LEU134 |
| A | TRP141 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 1Y1 B 301 |
| Chain | Residue |
| A | HOH501 |
| B | ALA97 |
| B | ASP100 |
| B | PHE101 |
| B | TYR105 |
| B | ASP108 |
| B | PHE109 |
| B | MET112 |
| B | LEU134 |
| B | TRP141 |
| B | GLY142 |
| B | ARG143 |
| B | ALA146 |
| B | GLU162 |
| B | SER164 |
| B | PRO165 |
| B | TYR199 |
| B | HOH406 |
| B | HOH518 |
| B | HOH524 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 19 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFeFGG |
| Chain | Residue | Details |
| A | LEU134-GLY152 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqdnGGWDaFV |
| Chain | Residue | Details |
| A | TRP185-VAL196 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VhltLRqAGDDFSRR |
| Chain | Residue | Details |
| A | VAL90-ARG104 | |
| site_id | PS01260 |
| Number of Residues | 21 |
| Details | BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. DNREIVmKYIHYKLSQRGYeW |
| Chain | Residue | Details |
| A | ASP8-TRP28 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Motif: {"description":"BH3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | Motif: {"description":"BH1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 30 |
| Details | Motif: {"description":"BH2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
