4M9T
NS2B-NS3 protease from dengue virus in the presence of DTNB, a covalent allosteric inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NS2B-NS3 protease | polymer | 247 | 26360.5 | 1 | UniProt (Q91H74) Pfam (PF01002) Pfam (PF00949) UniProt (by SIFTS) (P12823) | Dengue virus 2 | |
| 2 | B (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | C (A) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A: 49 - 95 (UniProt: Q91H74)
A: 1001 - 1177 (UniProt: Q91H74)
| PDB | External Database | Details |
|---|---|---|
| Gly 43 | - | expression tag |
| Ser 44 | - | expression tag |
| His 45 | - | expression tag |
| Met 46 | - | expression tag |
| Leu 47 | - | expression tag |
| Glu 48 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 96 | - | linker |
| Gly 993 | - | linker |
| Gly 994 | - | linker |
| Gly 995 | - | linker |
| Ser 996 | - | linker |
| Gly 997 | - | linker |
| Gly 998 | - | linker |
| Gly 999 | - | linker |
| Gly 1000 | - | linker |
| Cys 1125 | Ala 1600 | engineered mutation |
| Asn 1167 | Gln 1642 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26360.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 26395.9 |
