4M9T

NS2B-NS3 protease from dengue virus in the presence of DTNB, a covalent allosteric inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003724	molecular_function	RNA helicase activity
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005524	molecular_function	ATP binding
A	0044423	cellular_component	virion component

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 1201

Chain	Residue
A	LYS1042
A	GLU1086
A	VAL1146

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: Charge relay system; for serine protease NS3 activity => ECO:0000255|PROSITE-ProRule:PRU00860

Chain	Residue	Details
A	HIS1051
A	ASP1075
A	SER1135

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