4M8Q
Ontogeny of recognition specificity and functionality for the anti-HIV neutralizing antibody 4E10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, H) | GEP1 Fv heavy chain | polymer | 129 | 13656.3 | 2 | Homo sapiens (human) | ||
| 2 | B, E (B, L) | GEP1 Fv light chain | polymer | 113 | 12211.6 | 2 | UniProt (P18136) Pfam (PF07686) UniProt (by SIFTS) (P01619) | Homo sapiens (human) | Ig kappa chain V-III region HIC |
| 3 | C, F (C, S) | 4E10 epitope scaffold T117 | polymer | 161 | 18446.8 | 2 | synthetic construct |
Sequence modifications
B, L: 1 - 108 (UniProt: P18136)
| PDB | External Database | Details |
|---|---|---|
| Ser 96 | Trp 117 | conflict |
| Leu 109 | - | expression tag |
| Val 110 | - | expression tag |
| Pro 111 | - | expression tag |
| Arg 112 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 88629.5 | |
| All* | Total formula weight | 88629.5 |
