4M7V
Dihydrofolate reductase from Enterococcus faecalis complexed with NADP(H)and RAB-propyl
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydrofolate reductase | polymer | 175 | 19916.6 | 1 | UniProt (Q834R2) Pfam (PF00186) | Enterococcus faecalis | |
| 2 | B (A) | 5-(3,4-dimethoxy-5-{(1E)-3-oxo-3-[(1S)-1-propylphthalazin-2(1H)-yl]prop-1-en-1-yl}benzyl)pyrimidine-2,4-diamine | non-polymer | 486.6 | 1 | Chemie (RAR) | |||
| 3 | C (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 4 | D (A) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A: 1 - 163 (UniProt: Q834R2)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Leu 164 | - | expression tag |
| Val 165 | - | expression tag |
| Pro 166 | - | expression tag |
| Arg 167 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19916.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1230.0 | |
| All* | Total formula weight | 21146.6 |
