4M78

Crystal structure of Lsm2-8 complex, space group P21

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, H	U6 snRNA-associated Sm-like protein LSm8	polymer	96	10722.3	2	UniProt (P47093) Pfam (PF01423) In PDB	Saccharomyces cerevisiae (Baker's yeast)
2	B, I	U6 snRNA-associated Sm-like protein LSm2	polymer	95	11161.8	2	UniProt (P38203) Pfam (PF01423) In PDB	Saccharomyces cerevisiae (Baker's yeast)	Small nuclear ribonucleoprotein D homolog SNP3
3	C, J	U6 snRNA-associated Sm-like protein LSm3	polymer	89	10007.1	2	UniProt (P57743) Pfam (PF01423) In PDB	Saccharomyces cerevisiae (Baker's yeast)	SmX4 protein
4	D, K	U6 snRNA-associated Sm-like protein LSm6	polymer	86	9406.6	2	UniProt (Q06406) Pfam (PF01423) In PDB	Saccharomyces cerevisiae (Baker's yeast)
5	E, L	U6 snRNA-associated Sm-like protein LSm5	polymer	93	10433.0	2	UniProt (P40089) Pfam (PF01423) In PDB	Saccharomyces cerevisiae (Baker's yeast)
6	F, M	U6 snRNA-associated Sm-like protein LSm7	polymer	115	13027.0	2	UniProt (P53905) Pfam (PF01423) In PDB	Saccharomyces cerevisiae (Baker's yeast)
7	G, N	U6 snRNA-associated Sm-like protein LSm4	polymer	93	10627.1	2	UniProt (P40070) Pfam (PF01423) In PDB	Saccharomyces cerevisiae (Baker's yeast)
8		water	water		18.0	53	Chemie (HOH)

Sequence modifications

A, H: 1 - 96 (UniProt: P47093)

PDB	External Database	Details
Leu 17	Lys 17	engineered mutation
Ser 22	Cys 22	engineered mutation
Leu 38	Ile 38	engineered mutation
Ser 51	Cys 51	engineered mutation

B, I: 1 - 95 (UniProt: P38203)

PDB	External Database	Details
Ser 45	Cys 45	engineered mutation

C, J: 1 - 89 (UniProt: P57743)

PDB	External Database	Details
Ser 37	Cys 37	engineered mutation
Ser 63	Cys 63	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	14
	Total formula weight	150769.9
All*	Total formula weight	150769.9

*Water molecules are not included.