4M76
Integrin I domain of complement receptor 3 in complex with C3d
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Complement C3 | polymer | 298 | 33199.0 | 1 | UniProt (P01024) Pfam (PF07678) In PDB | Homo sapiens (human) | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, Complement C3 beta chain, Complement C3 alpha chain, C3a anaphylatoxin, Acylation stimulating protein, ASP, C3adesArg, Complement C3b alpha' chain, Complement C3c alpha' chain fragment 1, Complement C3dg fragment, Complement C3g fragment, Complement C3d fragment, Complement C3f fragment, Complement C3c alpha' chain fragment 2 |
2 | B | Integrin alpha-M | polymer | 198 | 22480.6 | 1 | UniProt (P11215) Pfam (PF00092) In PDB | Homo sapiens (human) | CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor |
3 | A, B | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
4 | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 994 - 1288 (UniProt: P01024)
B: 127 - 321 (UniProt: P11215)
PDB | External Database | Details |
---|---|---|
Gly 991 | - | expression tag |
Ala 992 | - | expression tag |
Met 993 | - | expression tag |
Ala 1010 | Cys 1010 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 124 | - | expression tag |
Ala 125 | - | expression tag |
Met 126 | - | expression tag |
Ser 128 | Cys 144 | engineered mutation |
Gly 316 | Ile 332 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 55679.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 117.4 | |
All* | Total formula weight | 55797.0 |