4M63
Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | T3SS2 effector VopL nucleation of actin polymerization | polymer | 241 | 26816.1 | 2 | UniProt (L0I5A1) In PDB | Vibrio parahaemolyticus | |
2 | C, D, E | Actin-5C | polymer | 377 | 41808.8 | 3 | UniProt (P10987) Pfam (PF00022) In PDB | Drosophila melanogaster (Fruit fly) | |
3 | C, D, E | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) | |||
4 | C, D, E | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) |
Sequence modifications
A, B: 247 - 484 (UniProt: L0I5A1)
C, D, E: 0 - 375 (UniProt: P10987)
PDB | External Database | Details |
---|---|---|
Gly 244 | - | expression tag |
His 245 | - | expression tag |
Met 246 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ala 286 | Asp 287 | engineered mutation |
Ala 287 | Val 288 | engineered mutation |
Ala 288 | Asp 289 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 179058.5 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1641.8 | |
All* | Total formula weight | 180700.3 |