4M4S
Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in complex with GDP and formate ion mimic aIF2gamma*GDP*Pi complex (a formate ion substitutes for Pi)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Translation initiation factor 2 subunit gamma | polymer | 415 | 45628.9 | 1 | UniProt (Q980A5) Pfam (PF00009) Pfam (PF09173) | Sulfolobus solfataricus | aIF2-gamma, eIF-2-gamma |
| 2 | AA, B, BA, C, CA... (A) | FORMIC ACID | non-polymer | 46.0 | 29 | Chemie (FMT) PubChem (284) | |||
| 3 | EA (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | FA, GA (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | HA, IA, JA, KA (A) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) PubChem (923) | |||
| 6 | LA (A) | water | water | 18.0 | 437 | Chemie (HOH) |
Sequence modifications
A: 1 - 415 (UniProt: Q980A5)
| PDB | External Database | Details |
|---|---|---|
| Ala 221 | Phe 221 | engineered mutation |
| Ala 225 | Lys 225 | engineered mutation |
| Ala 280 | Arg 280 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45628.9 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 1918.5 | |
| All* | Total formula weight | 47547.4 |
