4M2T
Corrected Structure of Mouse P-glycoprotein bound to QZ59-SSS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Multidrug resistance protein 1A | polymer | 1282 | 141677.7 | 2 | UniProt (P21447) Pfam (PF00664) Pfam (PF00005) | Mus musculus (mouse) | ATP-binding cassette sub-family B member 1A, MDR1A, Multidrug resistance protein 3, P-glycoprotein 3 |
| 2 | C, D, E, F (A, B) | (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione | non-polymer | 687.4 | 4 | Chemie (2J8) |
Sequence modifications
A, B: 1 - 1276 (UniProt: P21447)
| PDB | External Database | Details |
|---|---|---|
| Gln 83 | Asn 83 | conflict |
| Gln 87 | Asn 87 | conflict |
| Gln 90 | Asn 90 | conflict |
| His 1277 | - | expression tag |
| His 1278 | - | expression tag |
| His 1279 | - | expression tag |
| His 1280 | - | expression tag |
| His 1281 | - | expression tag |
| His 1282 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 283355.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2749.7 | |
| All* | Total formula weight | 286105.0 |
