4M2B
Crystal structure of L281D mutant of udp-glucose pyrophosphorylase from leishmania major in complex with udp-glc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-glucose pyrophosphorylase | polymer | 505 | 56056.7 | 1 | UniProt (Q4QDU3) Pfam (PF01704) | Leishmania major | |
| 2 | B (A) | URIDINE-5'-DIPHOSPHATE-GLUCOSE | non-polymer | 566.3 | 1 | Chemie (UPG) PubChem (16667381) PubChem (20776702) PubChem (20776703) PubChem (1166) PubChem (16760700) PubChem (439156) PubChem (20776705) PubChem (25011746) PubChem (20776706) PubChem (23724458) PubChem (448801) PubChem (45109771) PubChem (46226441) PubChem (46936243) PubChem (53477679) PubChem (56845790) PubChem (58538034) PubChem (59720988) PubChem (56650783) PubChem (56846106) PubChem (8629) PubChem (18068) PubChem (88869506) PubChem (88869507) PubChem (88869743) PubChem (88870643) PubChem (88883029) PubChem (88910951) PubChem (88941526) PubChem (89321600) PubChem (89360378) PubChem (6857540) PubChem (89847362) PubChem (90056247) PubChem (439158) PubChem (90950359) PubChem (91746280) PubChem (448873) PubChem (640055) PubChem (92974126) PubChem (92974128) PubChem (92974129) PubChem (93535589) PubChem (12133414) PubChem (13008857) PubChem (13987142) PubChem (92328335) PubChem (92974127) PubChem (6857410) PubChem (124933210) PubChem (102429624) PubChem (129850353) PubChem (11734460) PubChem (124933209) PubChem (134736387) PubChem (134736388) PubChem (155893098) PubChem (158571248) PubChem (162920685) PubChem (138911444) PubChem (168265389) PubChem (162920683) PubChem (162920684) PubChem (163626061) PubChem (166642644) PubChem (168720052) PubChem (174027848) | |||
| 3 | C (A) | water | water | 18.0 | 393 | Chemie (HOH) |
Sequence modifications
A: 1 - 494 (UniProt: Q4QDU3)
| PDB | External Database | Details |
|---|---|---|
| Asp 281 | Leu 281 | engineered mutation |
| Met 495 | - | expression tag |
| Arg 496 | - | expression tag |
| Pro 497 | - | expression tag |
| Leu 498 | - | expression tag |
| Glu 499 | - | expression tag |
| His 500 | - | expression tag |
| His 501 | - | expression tag |
| His 502 | - | expression tag |
| His 503 | - | expression tag |
| His 504 | - | expression tag |
| His 505 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 56056.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 566.3 | |
| All* | Total formula weight | 56623.0 |
