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4M10

Crystal Structure of Murine Cyclooxygenase-2 Complex with Isoxicam

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DProstaglandin G/H synthase 2polymer58767332.74UniProt (Q05769)
Pfam (PF00008)
Pfam (PF03098)
In PDB
Mus musculus (mouse)Cyclooxygenase-2, COX-2, Glucocorticoid-regulated inflammatory cyclooxygenase, Gripghs, Macrophage activation-associated marker protein P71/73, PES-2, PHS II, Prostaglandin H2 synthase 2, PGH synthase 2, PGHS-2, Prostaglandin-endoperoxide synthase 2, TIS10 protein
2E, F, G, H2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.44In PDB
GlyTouCan (G42666HT)
3A, B, C, D2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.28Chemie (NAG)
4A, B, C, DPROTOPORPHYRIN IX CONTAINING FEnon-polymer616.54Chemie (HEM)
5D, A, B, C4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxidenon-polymer335.34Chemie (ICD)
6D, B, Coctyl beta-D-glucopyranosidenon-polymer292.44Chemie (BOG)
7waterwater18.01738Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight269330.8
BranchedNumber of molecules4
Total formula weight1697.6
Non-Polymers*Number of molecules20
Total formula weight6746.4
All*Total formula weight277774.9
*Water molecules are not included.

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PDB entries from 2024-03-27

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