4LZ1
X-ray structure of the complex between human thrombin and the TBA deletion mutant lacking thymine 12 nucleobase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Thrombin light chain | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain |
| 2 | B (H) | Thrombin heavy chain | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin heavy chain |
| 3 | C (D) | Thrombin Binding Aptamer | polymer | 15 | 4619.0 | 1 | |||
| 4 | D (L) | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 1 | BIRD (PRD_000020) Chemie (0G6) | |||
| 5 | E (H) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 6 | F (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | G (H) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 8 | H, I, J (L, H, D) | water | water | 18.0 | 229 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 38495.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 737.3 | |
| All* | Total formula weight | 39233.0 |
