4LXZ
Structure of Human HDAC2 in complex with SAHA (vorinostat)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Histone deacetylase 2 | polymer | 369 | 42367.2 | 3 | UniProt (Q92769) Pfam (PF00850) | Homo sapiens (human) | HD2 |
| 2 | D, K, S (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | E, L, T (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 4 | F, M, U (A, B, C) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 5 | G, H, I, O, P... (A, B, C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 8 | Chemie (PG4) | |||
| 6 | J, R, X (A, B, C) | OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE | non-polymer | 264.3 | 3 | Chemie (SHH) | |||
| 7 | N (B) | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID | non-polymer | 207.3 | 1 | Chemie (NHE) | |||
| 8 | AA, Y, Z (C, A, B) | water | water | 18.0 | 923 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 127101.7 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 2939.5 | |
| All* | Total formula weight | 130041.2 |
