Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004407 | molecular_function | histone deacetylase activity |
| B | 0004407 | molecular_function | histone deacetylase activity |
| C | 0004407 | molecular_function | histone deacetylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | ASP181 |
| A | HIS183 |
| A | ASP269 |
| A | SHH407 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 402 |
| Chain | Residue |
| A | ASP179 |
| A | ASP181 |
| A | HIS183 |
| A | SER202 |
| A | PHE203 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 403 |
| Chain | Residue |
| A | PHE192 |
| A | THR195 |
| A | VAL198 |
| A | TYR227 |
| A | HOH522 |
| A | HOH528 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PG4 A 404 |
| Chain | Residue |
| A | LYS71 |
| A | ALA191 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PG4 A 405 |
| Chain | Residue |
| A | ARG311 |
| A | GLU340 |
| A | TYR341 |
| A | GLY343 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG4 A 406 |
| Chain | Residue |
| A | ASP23 |
| A | ASN26 |
| A | TYR27 |
| A | ASP109 |
| A | HOH802 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SHH A 407 |
| Chain | Residue |
| A | PRO34 |
| A | ASP104 |
| A | HIS145 |
| A | HIS146 |
| A | GLY154 |
| A | PHE155 |
| A | ASP181 |
| A | HIS183 |
| A | ASP269 |
| A | TYR308 |
| A | ZN401 |
| A | HOH606 |
| A | HOH791 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 401 |
| Chain | Residue |
| B | ASP181 |
| B | HIS183 |
| B | ASP269 |
| B | SHH408 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 402 |
| Chain | Residue |
| B | ASP179 |
| B | ASP181 |
| B | HIS183 |
| B | SER202 |
| B | PHE203 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 403 |
| Chain | Residue |
| B | PHE192 |
| B | THR195 |
| B | VAL198 |
| B | TYR227 |
| B | HOH533 |
| B | HOH549 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NHE B 404 |
| Chain | Residue |
| A | TYR59 |
| A | LYS128 |
| B | ASP21 |
| B | ASP23 |
| B | ARG60 |
| B | LYS63 |
| B | GLU113 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG4 B 405 |
| Chain | Residue |
| B | ARG311 |
| B | GLU340 |
| B | TYR341 |
| B | GLY343 |
| B | HOH835 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG4 B 406 |
| Chain | Residue |
| B | LYS284 |
| B | ASN331 |
| B | HIS349 |
| C | GLU67 |
| C | THR70 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 B 407 |
| Chain | Residue |
| A | ARG131 |
| B | ASP23 |
| B | ASN26 |
| B | TYR27 |
| B | ASP109 |
| B | GLU113 |
| site_id | BC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SHH B 408 |
| Chain | Residue |
| B | PRO34 |
| B | ASP104 |
| B | HIS145 |
| B | HIS146 |
| B | GLY154 |
| B | ASP181 |
| B | HIS183 |
| B | ASP269 |
| B | TYR308 |
| B | ZN401 |
| B | HOH671 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 401 |
| Chain | Residue |
| C | ASP181 |
| C | HIS183 |
| C | ASP269 |
| C | SHH406 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA C 402 |
| Chain | Residue |
| C | ASP179 |
| C | ASP181 |
| C | HIS183 |
| C | SER202 |
| C | PHE203 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C 403 |
| Chain | Residue |
| C | VAL198 |
| C | TYR227 |
| C | HOH505 |
| C | HOH520 |
| C | PHE192 |
| C | THR195 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 C 404 |
| Chain | Residue |
| B | PRO344 |
| B | ASP345 |
| C | ALA191 |
| C | ARG197 |
| C | HOH540 |
| C | HOH627 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG4 C 405 |
| Chain | Residue |
| B | ASN354 |
| C | LEU169 |
| C | TYR171 |
| C | GLN173 |
| C | ARG197 |
| site_id | CC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SHH C 406 |
| Chain | Residue |
| C | PRO34 |
| C | ASP104 |
| C | HIS145 |
| C | HIS146 |
| C | GLY154 |
| C | ASP181 |
| C | HIS183 |
| C | ASP269 |
| C | TYR308 |
| C | HIS380 |
| C | ZN401 |
| C | HOH641 |
| C | HOH755 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS146 | |
| B | HIS146 | |
| C | HIS146 | |
| Chain | Residue | Details |
| A | ASP179 | |
| B | ASP179 | |
| B | ASP181 | |
| B | HIS183 | |
| B | PHE192 | |
| B | THR195 | |
| B | VAL198 | |
| B | SER202 | |
| B | PHE203 | |
| B | ASP269 | |
| C | ASP179 | |
| A | ASP181 | |
| C | ASP181 | |
| C | HIS183 | |
| C | PHE192 | |
| C | THR195 | |
| C | VAL198 | |
| C | SER202 | |
| C | PHE203 | |
| C | ASP269 | |
| A | HIS183 | |
| A | PHE192 | |
| A | THR195 | |
| A | VAL198 | |
| A | SER202 | |
| A | PHE203 | |
| A | ASP269 | |
| Chain | Residue | Details |
| A | TYR227 | |
| B | TYR227 | |
| C | TYR227 | |
| Chain | Residue | Details |
| A | LYS79 | |
| B | LYS79 | |
| C | LYS79 | |
| Chain | Residue | Details |
| A | LYS225 | |
| B | LYS225 | |
| C | LYS225 | |
| Chain | Residue | Details |
| A | CYS266 | |
| A | CYS278 | |
| B | CYS266 | |
| B | CYS278 | |
| C | CYS266 | |
| C | CYS278 | |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS79 | |
| B | LYS79 | |
| C | LYS79 | |
