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4LSU

Crystal structure of broadly and potently neutralizing antibody VRC-PG20 in complex with HIV-1 clade A/E 93TH057 gp120

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(G)
HIV-1 CLADE A/E STRAIN 93TH057 GP120polymer35339211.41Pfam (PF00516)
UniProt (by SIFTS) (Q0ED31)
Human immunodeficiency virus 1
2B
(H)
HEAVY CHAIN OF ANTIBODY VRC-PG20polymer22725258.51Homo sapiens
3C
(L)
LIGHT CHAIN OF ANTIBODY VRC-PG20polymer20421582.81Homo sapiens
4D, E, F, G, H...
(G)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.210Chemie (NAG)
5N
(G)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
6O, P, Q, R, T
(G, H, L)
1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
7S
(H)
CHLORIDE IONnon-polymer35.51Chemie (CL)
8U, V, W
(G, H, L)
waterwater18.0234Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight86052.8
Non-Polymers*Number of molecules17
Total formula weight2796.2
All*Total formula weight88848.9
*Water molecules are not included.

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PDB entries from 2024-10-30

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