4LSS
Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 clade A strain KER_2018_11 gp120
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | envelope glycoprotein GP120 | polymer | 359 | 39828.9 | 1 | Pfam (PF00516) UniProt (by SIFTS) (Q3ZLH8) | Human immunodeficiency virus 1 | |
| 2 | B (H) | HEAVY CHAIN OF ANTIBODY VRC01 | polymer | 224 | 24395.7 | 1 | Homo sapiens | ||
| 3 | C (L) | LIGHT CHAIN OF ANTIBODY VRC01 with N72T mutation | polymer | 210 | 23159.7 | 1 | Homo sapiens | ||
| 4 | D, E, F, G, H... (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 5 | P, T (G, H) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 6 | Q (G) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 7 | R, S, U (G, L) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 8 | V, W, X (G, H, L) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87384.3 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3260.2 | |
| All* | Total formula weight | 90644.4 |
