4LSP
Crystal structure of broadly and potently neutralizing antibody VRC-CH31 in complex with HIV-1 clade A/E gp120 93TH057
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | HIV-1 CLADE A/E STRAIN 93TH057 GP120 | polymer | 353 | 39211.4 | 1 | UniProt (by SIFTS) (Q0ED31) | Human immunodeficiency virus 1 | |
| 2 | B (H) | HEAVY CHAIN OF ANTIBODY VRC-CH31 | polymer | 236 | 25571.7 | 1 | Homo sapiens | ||
| 3 | C (L) | LIGHT CHAIN OF ANTIBODY VRC-CH31 | polymer | 210 | 22853.3 | 1 | Homo sapiens | ||
| 4 | D (A) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E, F, G, H, I... (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) PubChem (24139) | |||
| 6 | HA, Q, R (L, G) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | BA, CA, DA, EA, FA... (H, L, G) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 8 | X, Y (G) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) PubChem (8117) | |||
| 9 | AA, GA, Z (G, H) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) PubChem (923) | |||
| 10 | JA, KA, LA (G, H, L) | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87636.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 31 |
| Total formula weight | 3906.6 | |
| All* | Total formula weight | 92129.6 |
