4LRM
EGFR D770_N771insNPG in complex with PD168393
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Epidermal growth factor receptor | polymer | 334 | 37900.7 | 5 | UniProt (P00533) Pfam (PF07714) | Homo sapiens (human) | Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 |
| 2 | F, G, H, I, J (A, B, C, D, E) | N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}propanamide | non-polymer | 371.2 | 5 | Chemie (YUN) | |||
| 3 | K, L, M, N, O (A, B, C, D, E) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 694 - 1025 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Gly 692 | - | expression tag |
| Ser 693 | - | expression tag |
| Asn 771 | - | insertion |
| Pro 772 | - | insertion |
| Gly 773 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 189503.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1856.2 | |
| All* | Total formula weight | 191359.7 |
