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4LRH

Crystal structure of human folate receptor alpha in complex with folic acid

Replaces:  4KEO
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Folate receptor alphapolymer21825543.98UniProt (P15328)
Pfam (PF03024)
Homo sapiens (human)FR-alpha, Adult folate-binding protein, FBP, Folate receptor 1, Folate receptor, adult, KB cells FBP, Ovarian tumor-associated antigen MOv18
2BA, FA, I, IA, M...
(F, G, A, H, B...)
FOLIC ACIDnon-polymer441.48Chemie (FOL)
3AA, CA, DA, EA, GA...
(E, F, G, A, H...)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.222Chemie (NAG)
4MA, NA, OA, PA, QA...
(A, B, C, D, E...)
waterwater18.0196Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 213 (UniProt: P15328)
PDBExternal DatabaseDetails
Thr 214-expression tag
Leu 215-expression tag
Val 216-expression tag
Pro 217-expression tag
Arg 218-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight204350.8
Non-Polymers*Number of molecules30
Total formula weight8397.8
All*Total formula weight212748.6
*Water molecules are not included.

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PDB entries from 2025-07-23

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