4LRH

Crystal structure of human folate receptor alpha in complex with folic acid

Replaces:  4KEO

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005542	molecular_function	folic acid binding
A	0061714	molecular_function	folic acid receptor activity
A	1904447	biological_process	folate import across plasma membrane
B	0005542	molecular_function	folic acid binding
B	0061714	molecular_function	folic acid receptor activity
B	1904447	biological_process	folate import across plasma membrane
C	0005542	molecular_function	folic acid binding
C	0061714	molecular_function	folic acid receptor activity
C	1904447	biological_process	folate import across plasma membrane
D	0005542	molecular_function	folic acid binding
D	0061714	molecular_function	folic acid receptor activity
D	1904447	biological_process	folate import across plasma membrane
E	0005542	molecular_function	folic acid binding
E	0061714	molecular_function	folic acid receptor activity
E	1904447	biological_process	folate import across plasma membrane
F	0005542	molecular_function	folic acid binding
F	0061714	molecular_function	folic acid receptor activity
F	1904447	biological_process	folate import across plasma membrane
G	0005542	molecular_function	folic acid binding
G	0061714	molecular_function	folic acid receptor activity
G	1904447	biological_process	folate import across plasma membrane
H	0005542	molecular_function	folic acid binding
H	0061714	molecular_function	folic acid receptor activity
H	1904447	biological_process	folate import across plasma membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	96
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23851396","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Lipidation: {"description":"GPI-anchor amidated serine","evidences":[{"source":"PubMed","id":"17566972","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7578066","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"23851396","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23934049","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	16
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"18780401","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23851396","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23934049","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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