4LQD
The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Toll/interleukin-1 receptor domain-containing adapter protein | polymer | 144 | 16008.3 | 1 | UniProt (P58753) Pfam (PF13676) | Homo sapiens (human) | TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88 adapter-like protein, MyD88-2 |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
A: 81 - 221 (UniProt: P58753)
| PDB | External Database | Details |
|---|---|---|
| Gly 78 | - | expression tag |
| Val 79 | - | expression tag |
| Asp 80 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16008.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 16100.4 |
