4LQC
The crystal structures of the Brucella protein TcpB and the TLR adaptor protein TIRAP show structural differences in microbial TIR mimicry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | TcpB | polymer | 148 | 16880.2 | 2 | UniProt (Q8YF53) Pfam (PF13676) | Brucella melitensis | |
| 2 | C, D (A, B) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A, B: 113 - 250 (UniProt: Q8YF53)
| PDB | External Database | Details |
|---|---|---|
| Ala 124 | Ser 124 | engineered mutation |
| Ile 127 | Ser 127 | engineered mutation |
| Ser 251 | - | expression tag |
| Ala 252 | - | expression tag |
| Trp 253 | - | expression tag |
| Ser 254 | - | expression tag |
| His 255 | - | expression tag |
| Pro 256 | - | expression tag |
| Gln 257 | - | expression tag |
| Phe 258 | - | expression tag |
| Glu 259 | - | expression tag |
| Lys 260 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33760.3 | |
| All* | Total formula weight | 33760.3 |
