4LOL
Crystal structure of mSting in complex with DMXAA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Stimulator of interferon genes protein | polymer | 188 | 21545.5 | 2 | UniProt (Q3TBT3) Pfam (PF15009) | Mus musculus (mouse) | mSTING, Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, MMITA, Transmembrane protein 173 |
| 2 | C, D (A) | (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid | non-polymer | 282.3 | 2 | Chemie (1YE) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A, B: 154 - 340 (UniProt: Q3TBT3)
| PDB | External Database | Details |
|---|---|---|
| Ser 153 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43090.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 564.6 | |
| All* | Total formula weight | 43655.5 |
