4LOK
Crystal structure of mSting in complex with c[G(3',5')pA(3',5')p]
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Stimulator of interferon genes protein | polymer | 188 | 21545.5 | 2 | UniProt (Q3TBT3) Pfam (PF15009) | Mus musculus (mouse) | mSTING, Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, MMITA, Transmembrane protein 173 |
| 2 | C (B) | 2-amino-9-[(2R,3R,3aR,5S,7aS,9R,10R,10aR,12R,14aS)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one | non-polymer | 674.4 | 1 | Chemie (1YD) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
A, B: 154 - 340 (UniProt: Q3TBT3)
| PDB | External Database | Details |
|---|---|---|
| Ser 153 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43090.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 674.4 | |
| All* | Total formula weight | 43765.3 |
