4LOI
Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(2',5')p]
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Stimulator of interferon genes protein | polymer | 188 | 21524.2 | 2 | UniProt (Q86WV6) Pfam (PF15009) | Homo sapiens (human) | hSTING, Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, hMITA, Transmembrane protein 173 |
| 2 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | D (B) | 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one | non-polymer | 674.4 | 1 | Chemie (1YC) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence modifications
A, B: 155 - 341 (UniProt: Q86WV6)
| PDB | External Database | Details |
|---|---|---|
| Ser 154 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43048.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 769.4 | |
| All* | Total formula weight | 43817.7 |
