4LMQ
Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C (D, F) | Stromal cell-derived factor 1 | polymer | 61 | 7202.5 | 2 | UniProt (P48061) Pfam (PF00048) | Homo sapiens (human) | SDF-1, hSDF-1, C-X-C motif chemokine 12, Intercrine reduced in hepatomas, IRH, hIRH, Pre-B cell growth-stimulating factor, PBSF, SDF-1-beta(3-72), SDF-1-alpha(3-67) |
2 | B, D (E, H) | hu30D8 Fab heavy chain | polymer | 221 | 23370.1 | 2 | Homo sapiens | ||
3 | E, F (I, L) | hu30D8 Fab light chain | polymer | 214 | 23533.2 | 2 | Homo sapiens (human) | ||
4 | G, H, I, J, K... (D, E, F, H, I...) | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 108211.6 | |
All* | Total formula weight | 108211.6 |